Wegovy
semaglutide
FDA-approved for chronic weight management. Once-weekly subcutaneous injection.
How it works
Semaglutide mimics a naturally occurring gut hormone (GLP-1) that the body releases after meals. It slows gastric emptying, reduces appetite-driven food cues, and supports the body's own satiety signaling.
How we use it
Wegovy is part of our GLP-1 Weight Optimization program for patients meeting FDA on-label criteria, BMI ≥ 30, or BMI ≥ 27 with at least one weight-related comorbidity. Continuity is a priority, you will see the same physician whenever clinically possible; 45-min initial visit, 30-min monthly check-ins, unlimited secure messaging in between.
What to expect
Once-weekly subcutaneous self-administered injection. Dose escalation follows the FDA-approved schedule: 0.25 mg → 0.5 mg → 1.0 mg → 1.7 mg → 2.4 mg, advancing approximately monthly per tolerance. Maintenance dose is 2.4 mg weekly.
Adverse effects and contraindications
- Nausea, often dose-related and most pronounced during titration
- Diarrhea
- Constipation
- Reduced appetite
- Fatigue in the first weeks
- Headache
- Injection-site irritation
- Dizziness
- Pancreatitis, discontinue if suspected
- Gallbladder events (cholelithiasis, cholecystitis)
- Severe GI events requiring hospitalization
- Thyroid C-cell tumors, boxed warning per the FDA label
- Personal or family history of medullary thyroid carcinoma or MEN-2 syndrome
- Pregnancy or planned pregnancy in the next 2 months
- Severe gastroparesis
What the literature says
Published trials of semaglutide for chronic weight management (the STEP program) report substantial mean weight reduction at one year. Effects depend on continued use; published data indicate partial weight regain after discontinuation. Vayra does not claim specific outcomes for any patient.
How it reaches you
Branded Wegovy is prescribed and dispensed through a separately licensed retail/specialty pharmacy partner. Your Vayra membership covers your physician relationship, lab review, and the full clinical practice; your medication is priced separately and shown with your total.
Begin a documented physician visit.
Prescribing is the outcome of a clinical encounter, not a checkout flow. Your assessment takes about eight minutes; nothing is billed until you and your physician agree on a protocol.
Begin assessmentEight minutes to start. A lifetime of difference.
A Vayra-affiliated physician reviews your case within 24 hours. No insurance billed. Cancel anytime, two taps.