Zepbound
tirzepatide
FDA-approved for chronic weight management and for obstructive sleep apnea in adults with obesity. Once-weekly subcutaneous injection.
How it works
Tirzepatide activates two appetite-regulating hormone receptors, GIP and GLP-1, instead of one. It slows gastric emptying, reduces appetite, and improves glucose handling.
How we use it
Zepbound is part of our GLP-1 Weight Optimization program for patients meeting on-label criteria for chronic weight management or obesity-related obstructive sleep apnea. Continuity is a priority, you will see the same physician whenever clinically possible; 45-min initial visit, 30-min monthly check-ins.
What to expect
Once-weekly subcutaneous self-administered injection. Dose escalation per the FDA-approved schedule: 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg, advancing approximately monthly per tolerance. Maintenance is individualized to 5, 10, or 15 mg weekly.
Adverse effects and contraindications
- Nausea, most pronounced during titration
- Diarrhea
- Constipation
- Reduced appetite
- Fatigue
- Headache
- Injection-site irritation
- Dyspepsia
- Pancreatitis, discontinue if suspected
- Gallbladder events
- Acute kidney injury secondary to volume depletion during severe vomiting
- Thyroid C-cell tumors, boxed warning per the FDA label
- Personal or family history of medullary thyroid carcinoma or MEN-2 syndrome
- Pregnancy or planned pregnancy in the next 2 months
- Severe gastroparesis
What the literature says
Published trials of tirzepatide for chronic weight management (the SURMOUNT program) report mean weight reduction at one year. As with all GLP-1 RA therapy, effects depend on continued use. Vayra does not claim specific outcomes.
How it reaches you
Branded Zepbound is prescribed and dispensed through a separately licensed retail/specialty pharmacy partner. Your medication is priced separately and shown with your total, alongside your physician care and lab review.
Begin a documented physician visit.
Prescribing is the outcome of a clinical encounter, not a checkout flow. Your assessment takes about eight minutes; nothing is billed until you and your physician agree on a protocol.
Begin assessmentEight minutes to start. A lifetime of difference.
A Vayra-affiliated physician reviews your case within 24 hours. No insurance billed. Cancel anytime, two taps.